The Kentucky-Tennessee American Studies Association (KTASA) serves the states of Kentucky and Tennessee. The organization seeks to support and foster the study of the history, society, and culture of the region and to bring those interested in the region together to explore its dynamics; and to encourage interdisciplinary research, publication, and teaching.

Members of the chapters include college and university faculty at all ranks, undergraduate and graduate students, secondary school teachers, public historians, as well as librarians, archivists, and curators.

ASA members residing in the region are automatically KTASA members, and members of the ASA from outside the region are welcome to join the chapter. Interested parties unaffiliated with the ASA may join the KTASA directly.

In the past, KTASA has hosted a two-day conference annually, generally at a central location. Recently, in cooperation with the Southern ASA chapter (SASA), KTASA has shifted to a biennial schedule with KTASA conferences planned for even-numbered years and SASA conferences planned for odd-numbered years.

KTASA also publishes Border States biennially.

Triennially, the KTASA awards the Richard Beale Davis—William Berge Book Prize for the monograph published during the period that best illuminates the history, society, and culture of our region.